Peregrine.Reason®

Structured disagreement to improve truth approximation
in medical decision-making

Structured disagreement to improve
truth approximation
in medical decision-making

Structured disagreement to improve
truth approximation
in medical decision-making

AI agents that debate to expose uncertainty and improve decision-making

AI agents that debate to expose uncertainty and improve decision-making

Concept

Most AI systems optimise for agreement.

We propagate disagreement.

That is where signal lives.

Problem

Clinical decisions are rarely simple. Guidelines standardise care, but complex cases expose uncertainty.

MDTs are essential, but they can be slow, inconsistent, and vulnerable to groupthink.

System

Input → Independent Agents → Structured Debate → Moderation → Revision → Synthesis

Clinical focus

Built first for cancer MDT decision-making. Initial domain: Thyroid cancer.

Architecture

Multiple independent agents reason from the same case. They challenge assumptions.

A moderator evaluates competing arguments. The system produces a structured synthesis for clinician review.

Decision position

Clinical decision support. Not autonomous diagnosis. Clinician remains responsible.

Validation

Designed for real MDT cases. Initial testing with thyroid cancer clinicians.

Focus on uncertainty detection, reasoning transparency, and clinical usefulness.

Positioning

Not a chatbot.

Not diagnostic AI. Not a guideline engine.

A clinical reasoning architecture.

A new reasoning layer for multidisciplinary medicine.

Peregrine.Reason

Concept

System

Clinical

Company

Architecture

Validation

Positioning